Ann R Coll Surg Engl. Oct;97(7):e doi: /rcsann Doege-Potter Syndrome. Ahluwalia N(1), Attia R(1), Green A(1), Cane P(1). Doege-Potter syndrome presenting with hypoinsulinemic hypoglycemia in a patient with a malignant extrapleural solitary fibrous tumor: a case. We described here a patient with an SFTP with Doege-Potter syndrome who was successfully treated with complete resection. Although lesions.

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Doege—Potter syndrome DPSa paraneoplastic syndrome, presents as a hypoinsulinemic hypoglycemia from the ectopic secretion of insulin-like growth factor Pottr from a solitary fibrous tumor which may be intrapleural or extrapleural in origin. Several features of this site will not function whilst javascript is disabled. Solitary fibrous tumors of the soft tissues: J Postgrad Med ; Received 20 May The hypothesis of insulinoma was ruled out by the low insulin serum levels, and hypoinsulinemic hypoglycemia was characterized.

By accessing the work you hereby accept the Terms. The white arrow indicates a nodular area with marked low signal intensity on Syndromd image, which might correspond to a dense fibrotic stroma. The patient utilized prednisone for glycemic control and underwent percutaneous biopsy and later surgical intervention. Published 16 August Volume Clinically, many times, such tumor synrome as an asymptomatic slow-growing mass, frequently occurring in middle-aged individuals, with no predilection for sex 5 – 7.

Insulin like growth factors and cancer.

Management of non-islet-cell tumor hypoglycemia: At CT, SFT generally is seen as a circumscribed, lobulated, hypervascular mass, either displacing or compressing adjacent structures.

Coronal MRI T2-weighted HASTE image reveals a voluminous retroperitoneal, lobulated lesion with two distinctive portions, the upper portion more syhdrome, with foci of high signal intensity on T2-weighted image and the lower portion with intermediate and less heterogeneous signal intensity. Surgically cured hypoglycemia secondary to pleural solitary fibrous tumor: Find articles by Leandro Accardo Mattos. It may cause pain and symptoms resulting from adjacent structures compression 5.


In order to provide our website visitors and registered zyndrome with snydrome service tailored to their individual preferences we use cookies to analyse visitor traffic and personalise content. Iodinated contrast-enhanced CT portal phase — coronal reconstruction — identifies a large sjndrome, heterogeneous mass with two main portions. The lower portion of the mass is less vascularized.

Axial MRI T1-weighted image with fat saturation after intravenous contrast gadolinium injection in the region of the upper portion of the lesion shows findings similar to the ones observed at CT.

Doege-Potter syndrome: A review of the literature including a new case report.

Non-islet cell tumor-induced hypoglycemia: Blunting of costophrenic angle on right side, either due to residual pleural effusion or pleural change.

Localized benign and malignant fibrous tumors of the pleura. Neither calcification pogter fat were observed. Malignant SFTs dowge typically large, presenting areas of necrosis and hemorrhage in addition to cellular atypia and a high number of mitotic figures 5. Imaging features of solitary fibrous tumors. Hypoglycemia mediated by paraneoplastic production of insulin like growth factor-2 from a malignant renal solitary fibrous tumor – clinical case and literature review.

Doege-Potter Syndrome.

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Journals Why Publish With Us? Editor who approved publication: Low doses of prednisone were ineffective at relieving hypoglycemia. For permission for commercial use of this work, please see paragraphs 4.


Rev Pneumol Clin ; N Engl J Med ; Please review our privacy policy. We also retain data in relation to our visitors and registered users for internal purposes and for sharing information with our business partners. Minimal passive right pleural effusion Click here to view.

Doege-Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the | IMCRJ

Complete tumor resection remained the only definitive treatment. Find articles by Ricardo Francisco Tavares Romano. SFT is a rare neoplasia and, in spite of its originally described pleural origin, it may occur in any site of the body 5 – 8.

Fibrosarcoma of the mediastinum. A male, year-old patient admitted because of a progressive increase of the abdominal volume for five months, in association sgndrome daily episodes of sudden sweating with syncope. At admission, hypoglycemic episodes were characterized. Serum high molecular weight form of insulin-like growth factor II from patients with non-islet cell tumor hypoglycemia is O-glycosylated.

None, Conflict of Interest: Taken together, the tumor is most consistent with a synndrome solitary fibrous tumor Click here to view. How to cite this article: The lower portion of the lesion presented diffusion restriction.

Glucocorticoid therapy ameliorated hypoglycemia soege insulin-like growth factor-II producing solitary fibrous tumor. The effect of neoadjuvant treatment, consisting of chemoradiation, and consecutive selective embolization of vessels feeding the tumor were not identified.

A clinicopathologic review of cases. Iodinated contrast enhanced CT portal phase — axial section — shows the region of the upper portion of the mass with heterogeneous density and enhancement.